Send to

Choose Destination
Nutr Rev. 2010 Mar;68(3):178-81. doi: 10.1111/j.1753-4887.2010.00274.x.

Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation?

Author information

Vitamin K Laboratory, USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachussetts 02111, USA.


Numerous risk factors for instability of oral anticoagulation have been identified, including variability in vitamin K intake. However, few studies have directly tested the feasibility of manipulating dietary vitamin K to achieve stable oral anticoagulation. Recent findings from a randomized clinical trial suggest that dietary vitamin K manipulation is a viable option for managing stability of oral anticoagulant therapy. The approach appears to be effective for those patients who are under-anticoagulated and consume a small number of vitamin K-rich food sources. While an encouraging option for management of warfarin therapy, longer-term studies in different patient populations are required.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center