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Simul Healthc. 2010 Feb;5(1):8-15. doi: 10.1097/SIH.0b013e3181c91d4a.

The pharmacology of simulation: a conceptual framework to inform progress in simulation research.

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  • 1Simulation Technologies Program, Center for Experiential Learning and Assessment, Vanderbilt University School of Medicine, Center for Perioperative Research in Quality, Department of Anesthesiology, Vanderbilt University Medical Center, and Geriatric Education Research and Clinical Center, VA Tennessee Valley Healthcare System, Nashville, TN 37212, USA.


This article presents a framework for the design and evaluation of simulation research to assist in developing evidence on which to base decisions about curriculum design and implementation. Drawing on basic concepts in pharmacology, the article describes simulation learning experiences as analogous to a drug treatment. This leads to consideration of simulation pharmacokinetics and pharmacodynamics, dose-time curves, dose-effect relationships, and drug-drug interactions.

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