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Microbes Infect. 2010 Jul;12(7):518-27. doi: 10.1016/j.micinf.2010.03.013. Epub 2010 Apr 8.

Host responses to Candida albicans: Th17 cells and mucosal candidiasis.

Author information

1
University at Buffalo, SUNY, Department of Oral Biology, Buffalo, NY, USA.

Abstract

Candida albicans causes mucosal and disseminated candidiasis, which represent serious problems for the rapidly expanding immunocompromised population. Until recently, Th1-mediated immunity was thought to confer the primary protection, particularly for oral candidiasis. However, emerging data indicate that the newly-defined Th17 compartment appears to play the predominant role in mucosal candidiasis.

PMID:
20381638
PMCID:
PMC2892252
DOI:
10.1016/j.micinf.2010.03.013
[Indexed for MEDLINE]
Free PMC Article

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