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Epidemiol Infect. 2010 Dec;138(12):1789-95. doi: 10.1017/S0950268810000774. Epub 2010 Apr 12.

Alcohol consumption as a risk factor for pneumonia: a systematic review and meta-analysis.

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1
Public Health and Regulatory Policy, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. avsamokhvalov@yahoo.ca

Abstract

The aim of this study was to quantify the association between alcohol consumption and incidence of pneumonia and to examine possible pathways. This was done by a systematic review and meta-analyses on the dose-response relationship between alcohol consumption or alcohol-use disorders and the incidence of community-acquired pneumonia (CAP). The relative risk (RR) of CAP increased monotonically with increasing alcohol consumption. Individuals consuming 24, 60, and 120 g of pure alcohol daily demonstrated RRs for incident CAP of 1·12 (95% CI 1·02-1·23), 1·33 (95% CI 1·06-1·67) and 1·76 (95% CI 1·13-2·77), respectively, relative to non-drinkers. Clinically defined alcohol-use disorders were associated with an eightfold increased risk of CAP (RR 8·22, 95% CI 4·85-13·95). In conclusion, alcohol was found to be a risk factor for pneumonia with a clear statistical association, and a monotonic dose-response relationship.

PMID:
20380771
DOI:
10.1017/S0950268810000774
[Indexed for MEDLINE]

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