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Clin Infect Dis. 2010 May 15;50(10):1419-21. doi: 10.1086/652149.

Recognition of risk for clinically significant drug interactions among HIV-infected patients receiving antiretroviral therapy.

Author information

1
Department of Genitourinary Medicine, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.

Abstract

We assessed the risk of clinically significant drug interactions in patients receiving antiretrovirals, and their recognition by physicians. Clinically significant drug interactions were recorded in 27% of 159 patients, with 15% of interactions potentially lowering antiretroviral concentrations. Risk of clinically significant drug interactions was significantly related to receipt of protease inhibitors. Only 36% of clinically significant drug interactions were correctly identified by physicians.

PMID:
20380564
DOI:
10.1086/652149
[Indexed for MEDLINE]

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