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Lab Chip. 2010 Apr 7;10(7):824-7. doi: 10.1039/b926561a. Epub 2010 Feb 25.

Wide field-of-view lens-free fluorescent imaging on a chip.

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1
Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA.

Abstract

We demonstrate an on-chip fluorescent detection platform that can simultaneously image fluorescent micro-objects or labeled cells over an ultra-large field-of-view of 2.5 cm x 3.5 cm without the use of any lenses, thin-film filters and mechanical scanners. Such a wide field-of-view lensless fluorescent imaging modality, despite its limited resolution, might be very important for high-throughput screening applications as well as for detection and counting of rare cells within large-area microfluidic devices.

PMID:
20379564
PMCID:
PMC2863091
DOI:
10.1039/b926561a
[Indexed for MEDLINE]
Free PMC Article
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