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Fertil Steril. 2010 Dec;94(7):2507-13. doi: 10.1016/j.fertnstert.2010.02.037. Epub 2010 Apr 7.

Oocyte maturation failure: a syndrome of bad eggs.

Author information

1
Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Abstract

To show that disruption of meiotic competence results in cell cycle arrest, and the production of immature oocytes that are not capable of fertilization. Through an extensive review of animal studies and clinical case reports, we define the syndrome of oocyte maturation failure as a distinct oocyte disorder, present a classification system based on clinical parameters, and discuss the potential molecular origins for the disease.

PMID:
20378111
PMCID:
PMC2946974
DOI:
10.1016/j.fertnstert.2010.02.037
[Indexed for MEDLINE]
Free PMC Article

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