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Nat Rev Drug Discov. 2010 Apr;9(4):253-4. doi: 10.1038/nrd3144.

Anticancer drug development: the grand challenges.

Author information

1
Ortho Biotech Oncology Research and Development, 920 Route 202, Raritan, New Jersey 08869, USA. Whait@its.jnj.com

Abstract

Despite vast investment in oncology R&D, the translation of research advances into medicines that substantially improve the treatment of many cancers remains frustratingly slow. What are the key challenges in anticancer drug development, and how might they be addressed?

PMID:
20369394
DOI:
10.1038/nrd3144
[Indexed for MEDLINE]

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