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Sci Transl Med. 2009 Nov 18;1(7):7ps8. doi: 10.1126/scitranslmed.3000247.

Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification.

Author information

1
Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. jioannid@cc.uoi.gr

Abstract

Research standards deviate in genetic versus nongenetic epidemiology. Besides some immutable differences, such as the correlation pattern between variables, these divergent research standards can converge considerably. Current research designs that dissociate genetic and nongenetic measurements are reaching their limits. Studies are needed that massively measure genotypes, nongenetic exposures, and outcomes concurrently.

PMID:
20368180
DOI:
10.1126/scitranslmed.3000247
[Indexed for MEDLINE]

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