Send to

Choose Destination
Neuroimage. 2010 Sep;52(3):973-84. doi: 10.1016/j.neuroimage.2010.03.070. Epub 2010 Mar 31.

Dynamic brightness induction in V1: analyzing simulated and empirically acquired fMRI data in a "common brain space" framework.

Author information

Department of Neuroimaging and Neuromodeling, Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.


Computational neuromodeling may help to further our understanding of how empirical neuroimaging findings are generated by underlying neural mechanisms. Here, we used a simple computational model that simulates early visual processing of brightness changes in a dynamic, illusory display. The model accurately predicted illusory brightness changes in a grey area of constant luminance induced by (and in anti-phase to) luminance changes in its surroundings. Moreover, we were able to directly compare these predictions with recently observed fMRI results on the same brightness illusion by projecting predicted activity from our model onto empirically investigated brain regions. This new approach in which generated network activity and measured neuroimaging data are interfaced in a common representational "brain space" can contribute to the integration of computational and experimental neuroscience.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center