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Cleve Clin J Med. 2010 Apr;77(4):236-42. doi: 10.3949/ccjm.77a.09147.

Breaking the cycle of medication overuse headache.

Author information

1
Center for Headache and Pain, Neurological Institute, T33, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. teppers@ccf.org

Abstract

When patients who have frequent, disabling migraines take medications to relieve their symptoms, they run the risk that the attacks will increase in frequency to daily or near-daily as a rebound effect comes into play. This pattern, called medication overuse headache, is more likely to happen with butalbital and opioids than with migraine-specific drugs, as partial responses lead to recurrence, repeat dosing, and, eventually, overuse. Breaking the cycle involves weaning the patient from the overused medications, setting up a preventive regimen, and setting strict limits on the use of medications to relieve acute symptoms.

PMID:
20360117
DOI:
10.3949/ccjm.77a.09147
[Indexed for MEDLINE]
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