Send to

Choose Destination
See comment in PubMed Commons below
ACS Appl Mater Interfaces. 2009 Apr;1(4):811-5. doi: 10.1021/am800233s.

Nanostructured peptide fibrils formed at the organic-aqueous interface and their use as templates to prepare inorganic nanostructures.

Author information

  • 1Chemistry and Physics of Materials Unit, DST Nanoscience Unit and CSIR Centre of Excellence in Chemistry, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India.


Formation of fibril-type nanostructures of the Alzheimer's beta-amyloid diphenylalanine (l-Phe-l-Phe, FF) at the organic-aqueous interface and the factors affecting their structures have been investigated. Such nanostructures are also formed by bovine serum albumin and bovine pancreas insulin. The concentration of the precursor taken in the aqueous layer plays an important role in determining the morphology of the nanostructures. The addition of curcumin to the organic layer changes the structure of the self-assembled one-dimensional aggregates of diphenylalanine. By coating the diphenylalanine dipeptide fibrils with appropriate precursors followed by calcination in air, it has been possible to obtain one-dimensional nanostructures of inorganic materials.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center