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Future Microbiol. 2010 Apr;5(4):555-61. doi: 10.2217/fmb.10.31.

Chlamydia trachomatis: small genome, big challenges.

Author information

1
The Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Cambridge, UK. nrt@sanger.ac.uk

Abstract

Chlamydial infections are highly newsworthy, but basic research into Chlamydia trachomatis is severely hampered by a series of formidable technical barriers. This has resulted in a paucity of information with respect to the genetics and population structure of these recalcitrant bacteria. Here we present a review of what is currently known about the genomics of C. trachomatis and discuss the usefulness of molecular typing systems and the prospects of developing a pan-chlamydial genome resource.

PMID:
20353297
DOI:
10.2217/fmb.10.31
[Indexed for MEDLINE]

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