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Chem Cent J. 2010 Mar 29;4:8. doi: 10.1186/1752-153X-4-8.

Antibacterial mono- and sesquiterpene esters of benzoic acids from Iranian propolis.

Author information

1
Institute of Organic Chemistry with the Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria.

Abstract

BACKGROUND:

Propolis (bee glue) has been used as a remedy since ancient times. Propolis from unexplored regions attracts the attention of scientists in the search for new bioactive molecules.

RESULTS:

From Iranian propolis from the Isfahan province, five individual components were isolated: the prenylated coumarin suberosin 1, and four terpene esters: tschimgin (bornyl p-hydroxybenzoate) 2, tschimganin (bornyl vanillate) 3, ferutinin (ferutinol p-hydroxybenzoate) 4, and tefernin (ferutinol vanillate) 5. All of them were found for the first time in propolis. Compounds 2 - 5 demonstrated activity against Staphylococcus aureus.

CONCLUSIONS:

The results of the present study are consistent with the idea that propolis from unexplored regions is a promising source of biologically active compounds.

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