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J Nat Med. 2010 Jul;64(3):358-61. doi: 10.1007/s11418-010-0407-8. Epub 2010 Mar 27.

New flavonoids with 2BS cell proliferation promoting effect from the seeds of Trigonella foenum-graecum L.

Author information

1
Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China.

Abstract

Ten flavonoids were isolated from the ethyl acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum and their structures were elucidated on the basis of spectroscopic methods to be 5,7,3'-trihydroxy-5'-methoxylisoflavone (1), biochanin A (2), formononetin (3), irilone (4), tricin (5), daidzein (6), calycosin (7), orientin-2''-O-p-trans-coumarate (8), vitexin-2''-O-p-trans-coumarate (9), and tricin-7-O-beta-D: -glucopyranoside (10). Compounds 1 and 8 are new flavonoids, and 8 and 9 strongly promoted 2BS cell proliferation induced by H(2)O(2).

PMID:
20349151
DOI:
10.1007/s11418-010-0407-8
[Indexed for MEDLINE]

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