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Nat Rev Microbiol. 2010 May;8(5):340-9. doi: 10.1038/nrmicro2313. Epub 2010 Mar 29.

Medically important bacterial-fungal interactions.

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Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.


Whether it is in the setting of disease or in a healthy state, the human body contains a diverse range of microorganisms, including bacteria and fungi. The interactions between these taxonomically diverse microorganisms are highly dynamic and dependent on a multitude of microorganism and host factors. Human disease can develop from an imbalance between commensal bacteria and fungi or from invasion of particular host niches by opportunistic bacterial and fungal pathogens. This Review describes the clinical and molecular characteristics of bacterial-fungal interactions that are relevant to human disease.

[Indexed for MEDLINE]

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