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Microbes Infect. 2010 Jul;12(7):511-7. doi: 10.1016/j.micinf.2010.03.005. Epub 2010 Mar 27.

The innate immune response to Trypanosoma cruzi infection.

Author information

1
Laboratory of Immune Regulation, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka 565-0871, Japan.

Abstract

Trypanosoma cruzi infection is a major public health problem in Latin America. The host innate immune system plays a pivotal role in the recognition of T. cruzi infection and the subsequent development of adaptive immunity. In this review, we focus on the TLR-dependent and -independent innate immune responses to T. cruzi.

PMID:
20348008
DOI:
10.1016/j.micinf.2010.03.005
[Indexed for MEDLINE]

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