Format

Send to

Choose Destination
Ophthalmology. 2010 Jul;117(7):1423-9.e2. doi: 10.1016/j.ophtha.2009.11.028. Epub 2010 Mar 27.

The ocular pathology of Terson's syndrome.

Author information

1
The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

Abstract

PURPOSE:

To improve understanding of vision loss and clinical findings, we studied gross and microscopic pathology of retinas and optic nerves of individuals with Terson's syndrome.

DESIGN:

Retrospective case series with clinicopathologic correlation.

PARTICIPANTS:

We included 109 deceased individuals with Terson's syndrome.

METHODS:

Histologic sections and gross photographs from 109 cases of Terson's Syndrome, accessed from 1955 to 1992 at the Wm R. Green Laboratory of Ocular Pathology, were studied and photographed; a representative case is described in detail.

MAIN OUTCOME MEASURES:

Abnormalities in retina and optic nerve.

RESULTS:

Hemorrhages occur in vitreous, subhyaloid, sub-internal limiting membrane (ILM), intraretinal, and subretinal spaces, in association with macular holes, retinal detachments, and optic neuropathy. Subhyaloid hemorrhages have diffuse morphology, whereas sub-ILM are well-demarcated. Continuous and noncontinuous blood occurs along optic nerves, within nerve sheaths, and in the subdural and subarachnoid spaces.

CONCLUSIONS:

Blood occurring in various layers and locations of the retina, particularly the macula, causes various complications that influence clinical management and visual outcome. Morphology differentiates subhyaloid from sub-ILM hemorrhage. Patterns of hemorrhages of optic nerve contribute to understanding mechanisms of Terson's syndrome.

FINANCIAL DISCLOSURE(S):

The authors have no proprietary or commercial interest in any of the materials discussed in this article.

PMID:
20347154
DOI:
10.1016/j.ophtha.2009.11.028
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center