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Colorectal Dis. 2011 Jun;13(6):663-8. doi: 10.1111/j.1463-1318.2010.02270.x. Epub 2010 Mar 23.

Emergency presentation of colon cancer is most frequent during summer.

Author information

1
Department of Molecular Medicine and Surgery, Karolinska Institutet Centre for Clinical Research, Sörmland County Council, Nyköping, Sweden. Hanna.gunnarsson@ki.se

Abstract

AIM:

The frequency of emergency colon cancer (ECC) was determined using a reproducible definition of 'emergency' to analyse the impact of mode of presentation on long-term prognosis and to search for risk factors for an emergency presentation.

METHOD:

All patients with colon cancer treated at one Swedish GDH between 1996 and 2005 (N = 604) were eligible. Patients admitted through the emergency room, operated on within three days and with an emergency condition confirmed at surgery were classified as ECC. Survival was analysed by Kaplan-Meier estimates and risk of death by Cox regression.

RESULTS:

The rate of ECC was 97/585 (17%). Patients with ECC were older (median 77 vs 74, P = 0.02), they had more stage III and IV cancers (65%vs 47%; χ(2) = 9.4, P < 0.001) and had a cancer located in the caecum less often (20%vs 33%, χ(2) = 4.3 P = 0.04). ECC were most frequent between June and August (36%), whereas elective cases were evenly distributed throughout the year (χ(2) = 7.8; P = 0.049), Crude 5-year survival was 18% in ECC and 38% in the elective group (P < 0.001). The hazard ratio for death within five years in ECC, with 30-day mortality excluded and adjusted for age and sex was 2.25 (95% CI; 1.42-3.55).

CONCLUSION:

Emergency presentation of colon cancer is an independent and adverse risk factor for long-term survival. The causes of a seasonal variation need to be clarified.

[Indexed for MEDLINE]

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