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Mol Biol Rep. 2011 Jan;38(1):355-8. doi: 10.1007/s11033-010-0115-1. Epub 2010 Mar 26.

Localized expression pattern of miR-184 in Drosophila.

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Key Laboratory of Developmental Genes and Human Disease, Ministry of Education, Southeast University, Nanjing, 210009, People's Republic of China.


MicroRNAs (miRNAs) are a kind of endogenous non-coding small RNAs whose specific functions in animals are generally important. Although functions of some miRNAs have been identified, the role of miR-184 remains unknown. Here, we determined the temporal and spatial expression pattern of miR-184 during the different development stages and tissues in Drosophila. Strikingly, miR-184 is expressed ubiquitously in Drosophila embryos, larvae and adults, its expression pattern shows a dynamic changes during the development of embryo, especially in the central nervous system. This expression profile suggests that miR-184 may act important function in Drosophila development.

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