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Br Dent J. 2010 May 22;208(10):E20. doi: 10.1038/sj.bdj.2010.291. Epub 2010 Mar 26.

Periodontal disease might be associated even with impaired fasting glucose.

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The Center for Health Promotion and Preventive Medicine, Medical Corps, Israel Defense Forces, Jerusalem, Israel.



To determine whether there is an association between fasting plasma glucose level and periodontal condition in a non-diabetic male population.


Data of periodic medical examinations of 815 non-diabetic male adults (mean age 38.1 + or - 7.0 years) were analysed. Blood samples were drawn from each subject following a 14-hour fast. The distance between the cement-enamel-junction to alveolar bone crest was measured at inter-proximal sites on two standardised posterior bitewing radiographs.


Higher prevalence of alveolar bone loss was found among individuals with a fasting glucose level of > or = 100 mg/dL than among individuals with <100 mg/dL (p = 0.032) and among individuals with BMI > or = 25 than among individuals with BMI <25 (p = 0.025). Associations were found between bone loss prevalence and serum triglyceride levels of > or = 200mg/dL, total cholesterol level of > or = 200mg/dL and LDL-cholesterol level of > or = 130 mg/dL (p = 0.010, p <0.001, p = 0.009, respectively).


In the studied non-diabetic adult population, periodontal disease was associated with impaired glucose level. Periodontal disease could serve as a predictor for future diabetes mellitus, or play a possible role in the glucose imbalance and diabetes mellitus development.

[Indexed for MEDLINE]

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