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Diagn Microbiol Infect Dis. 2010 Jun;67(2):191-7. doi: 10.1016/j.diagmicrobio.2010.01.004. Epub 2010 Mar 24.

Activity of doripenem with and without levofloxacin, amikacin, and colistin against Pseudomonas aeruginosa and Acinetobacter baumannii.

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1
Department of Pathology, Hershey Medical Center, Hershey, PA 17033, USA.

Abstract

At 24 h, sub-MIC doripenem and levofloxacin showed synergy against 21 of 25 Pseudomonas aeruginosa strains, sub-MIC doripenem and amikacin against 22 isolates, and sub-MIC doripenem and colistin against 19 isolates. Of 25 Acinetobacter baumannii strains, sub-MIC doripenem and levofloxacin showed synergy against 11 strains at 24 h, sub-MIC doripenem and amikacin against 24 strains, and sub-MIC doripenem and colistin against all isolates.

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