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Nature. 2010 Mar 25;464(7288):513-9. doi: 10.1038/nature08981.

Lessons on longevity from budding yeast.

Author information

1
Department of Pathology, University of Washington, Seattle, Washington 98195, USA. kaeber@u.washington.edu

Erratum in

  • Nature. 2010 Apr 29;464(7293):1390.

Abstract

The past decade has seen fundamental advances in our understanding of the ageing process and raised optimism that interventions to slow ageing may be on the horizon. Studies of budding yeast have made immense contributions to this progress. Yeast longevity factors have now been shown to modulate ageing in invertebrate and mammalian models, and studies of yeast have resulted in some of the best candidates for anti-ageing drugs currently in development. The first interventions to slow human ageing may spring from the humble yeast.

PMID:
20336133
PMCID:
PMC3696189
DOI:
10.1038/nature08981
[Indexed for MEDLINE]
Free PMC Article

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