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Ophthalmic Surg Lasers Imaging. 2010 Mar-Apr;41(2):157-65. doi: 10.3928/15428877-20100303-02.

Visual outcomes in five different approaches for treatment of central retinal vein occlusion.

Author information

1
Ophthalmic Research Centre of Shaheed Beheshti Medical University, Labbafinejad Medical Centre, Tehran, Iran.

Abstract

BACKGROUND AND OBJECTIVE:

Four treatment methods for central retinal vein occlusion were compared with its natural course.

PATIENTS AND METHODS:

In this partially prospective, comparative, interventional case series on 63 eyes with central retinal vein occlusion, five approaches were compared: intravitreal triamcinolone injection; radial optic neurotomy; combined radial optic neurotomy and intraocular triamcinolone injection; combined internal limiting membrane peeling, radial optic neurotomy, and intraocular triamcinolone; and observation.

RESULTS:

Final visual acuity in the intravitreal triamcinolone group was better compared with the observation (P = .025), radial optic neurotomy (P = .037), combined radial optic neurotomy/intraocular triamcinolone injection (P = .401), and combined internal limiting membrane peeling, radial optic neurotomy, and intraocular triamcinolone injection (P = .023) groups. However, after adjustment for baseline visual acuity, the only treatment method with significant visual acuity improvement in relation to the observation group was the combined radial optic neurotomy/intraocular triamcinolone injection (P = .025, .023, and .054 at 1, 3, and 6 months, respectively).

CONCLUSION:

Among the five different approaches analyzed in this study, combined radial optic neurotomy and intraocular triamcinolone injection may provide a better visual outcome in the management of central retinal vein occlusion.

PMID:
20307032
DOI:
10.3928/15428877-20100303-02
[Indexed for MEDLINE]

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