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Virus Genes. 2010 Aug;41(1):1-4. doi: 10.1007/s11262-010-0472-9. Epub 2010 Mar 20.

Genetic analysis of the VP1 region of enterovirus 71 reveals the emergence of genotype A in central China in 2008.

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  • 1Department of Microbiology, Anhui Medical University, 230032, Hefei, Anhui, China.

Abstract

Enterovirus 71 (EV71) strains from children were characterized by full-length VP1 nucleotide sequencing. Out of 22 clinical specimens, five isolates identified as EV71 were recovered by virus isolation. The VP1 sequences of the five isolates had more than 97.4% sequence identity with prototype virus BrCr, clustering in the genotype A lineage. This represents the first record of genotype A EV71 in China since the BrCr prototype strain was discovered in the USA in 1969.

PMID:
20306124
DOI:
10.1007/s11262-010-0472-9
[PubMed - indexed for MEDLINE]
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