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Dtsch Arztebl Int. 2010 Mar;107(9):152-62. doi: 10.3238/arztebl.2010.0152. Epub 2010 Mar 5.

The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee.

Author information

1
Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universität Köln, Köln, Germany. joern.michael@uk-koeln.de

Erratum in

  • Dtsch Arztebl Int. 2010 Apr;107(16):294.

Abstract

BACKGROUND:

Osteoarthritis is the most common joint disease of adults worldwide. Its incidence rises with age. Both intrinsic and extrinsic risk factors promote its development. In men aged 60 to 64, the right knee is more commonly affected; in women, the right and left knees are affected with nearly equal frequency.

METHODS:

The PubMed, Medline, Embase and Cochrane Library databases were selectively searched for current studies (up to September 2009; case reports excluded) on the epidemiology, etiology, diagnosis, staging, and treatment of osteoarthritis of the knee. The search terms were "gonarthrosis," "prevention," "conservative treatment," "joint preservation," "physical activity," "arthroscopy," "osteotomy," "braces," "orthoses," and "osteoarthritis knee joint."

RESULTS AND CONCLUSION:

Osteoarthritis is not yet a curable disease, and its pathogenesis remains unclear. The best treatment for osteoarthritis of the knee is prevention. The goal of therapy is to alleviate clinical manifestations. The therapeutic spectrum ranges from physiotherapy and orthopedic aids to pharmacotherapy and surgery.

PMID:
20305774
PMCID:
PMC2841860
DOI:
10.3238/arztebl.2010.0152
[Indexed for MEDLINE]
Free PMC Article

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