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JACC Cardiovasc Interv. 2010 Mar;3(3):265-75. doi: 10.1016/j.jcin.2009.12.013.

Recommendations for successful training on methods of delivery of biologics for cardiac regeneration: a report of the International Society for Cardiovascular Translational Research.

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1
Mercy Gilbert Medical Center, Chandler Regional Medical Center, 3420 South Mercy Road, Gilbert, AZ 85297, USA. ndib@cardiostem.com

Abstract

The field of myocardial regeneration (angiogenesis and myogenesis) might prove to play an important role in the future management of cardiovascular disease. Stem cells are currently undergoing testing in Phase I and Phase II clinical trials. Methods of delivery will affect the outcome of such therapies, perhaps significantly. This document provides suggested guidance in 4 methods of delivery: endocardial, intracoronary, coronary sinus, and epicardial.

PMID:
20298983
DOI:
10.1016/j.jcin.2009.12.013
[Indexed for MEDLINE]
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