Survival of cadaveric renal transplant grafts from young donors and in young recipients

Pediatr Nephrol. 1991 Jan;5(1):152-7. doi: 10.1007/BF00852874.

Abstract

Evidence from multicenter registries has suggested that cadaveric renal graft survival is poorer when either the recipient or the donor is very young. We therefore analyzed our results from a single pediatric center. There was a significant correlation between greater recipient age and improved cadaveric graft (P = 0.002) and patient (P = 0.0009) survival. The age of the donor also appeared important, particularly in very young children, but became less so as donor age rose. Forty-four percent of recipients under 3 years old who received cadaveric kidneys from donors less than 4 years old lost their grafts as a result of renal thrombosis, ischemia, or technical problems, compared with only 3% of recipients over 9 years of age, whose grafts came from donors who were also over 9 years. The 1-year first cadaveric graft survival rates for these two age groups were 33% and 82% respectively. Our experience confirms the poor findings reported in very young recipients and with very young donors.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Cadaver
  • Child
  • Child, Preschool
  • Graft Survival*
  • Humans
  • Kidney Transplantation*