Higher expression levels of activation-induced cytidine deaminase distinguish hairy cell leukemia from hairy cell leukemia-variant and splenic marginal zone lymphoma

Leukemia. 2010 May;24(5):1084-6. doi: 10.1038/leu.2010.44. Epub 2010 Mar 18.

Authors

S L Hockley, A Morilla, M Else, C Dearden, D Catovsky, G J Morgan, E Matutes, D Gonzalez

PMID: 20237507
DOI: 10.1038/leu.2010.44

No abstract available

Publication types

Comparative Study
Letter

MeSH terms

Blotting, Western
Cell Differentiation
Cytidine Deaminase / genetics*
Cytidine Deaminase / metabolism
Genetic Variation*
Humans
Immunoglobulin Heavy Chains / genetics
Immunoglobulin Variable Region / genetics
Immunophenotyping
Leukemia, Hairy Cell / genetics*
Leukemia, Hairy Cell / metabolism
Leukemia, Hairy Cell / pathology
Lymphoma, B-Cell, Marginal Zone / genetics*
Lymphoma, B-Cell, Marginal Zone / metabolism
Lymphoma, B-Cell, Marginal Zone / pathology
Mutation / genetics
RNA, Messenger / genetics
RNA, Messenger / metabolism
Reverse Transcriptase Polymerase Chain Reaction
Splenic Neoplasms / genetics*
Splenic Neoplasms / metabolism
Splenic Neoplasms / pathology

Substances

Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
RNA, Messenger
AICDA (activation-induced cytidine deaminase)
Cytidine Deaminase