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J Perinatol. 2010 Dec;30(12):805-8. doi: 10.1038/jp.2010.38. Epub 2010 Mar 18.

High-flow nasal cannula and extubation success in the premature infant: a comparison of two modalities.

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1
Division of Newborn Medicine, Weill Cornell Medical College, New York, NY, USA.

Abstract

OBJECTIVE:

To compare the effectiveness of Fisher and Paykel (FP) and Vapotherm (VT) high-flow nasal cannula (HFNC) in preventing reintubation either within 72 h or <7 days after extubation of premature infants. The primary outcome was the rate of extubation failure defined as reintubation within 72 h. Secondary outcomes included reintubation after ≤7 days.

STUDY DESIGN:

This was a prospective, randomized pilot study comparing the extubation success of 40 infants born between 26 and 29 weeks of gestation.

RESULT:

The rate of extubation failure at 72 h was 18% for FP and 9% for VT. The failure rate ≤7 days after extubation was 30% for FP and 27% for VT. None of these differences were statistically significant.

CONCLUSION:

There was no difference between FP and VT in the extubation success of infants born between 26 and 29 weeks.

PMID:
20237485
DOI:
10.1038/jp.2010.38
[Indexed for MEDLINE]
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