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J Pediatr. 2010 Jun;156(6):948-52. doi: 10.1016/j.jpeds.2009.12.033. Epub 2010 Mar 16.

High prevalence of vitamin D deficiency among inner-city African American youth with asthma in Washington, DC.

Author information

  • 1Center for Genetic Medicine Research, Children's National Medical Center, Washington, DC 20010, USA. rfreishtat@cnmcresearch.org

Abstract

OBJECTIVE:

The goal of this study was to examine the prevalence of vitamin D insufficiency and deficiency among urban African-American (AA) youth with asthma compared with control subjects without asthma.

STUDY DESIGN:

A cross-sectional case-control study was conducted at an urban pediatric medical center. Total 25-hydroxyvitamin D insufficiency (<30 ng/mL) and deficiency (<20 ng/mL) were assessed in urban self-reported AA patients, aged 6 to 20 years, with (n = 92) and without (n = 21) physician-diagnosed asthma.

RESULTS:

Blood samples were available for 85 (92%) cases. The prevalence of vitamin D insufficiency and deficiency were significantly greater among cases than control subjects (73/85 [86%] vs 4/21 [19%], adjusted odds ratio = 42 [95% confidence interval: 4.4 to 399] for insufficiency and 46/85 [54%] vs 1/21 [5%], adjusted odds ratio = 20 [95% confidence interval: 1.4 to 272] for deficiency).

CONCLUSIONS:

Most of this sample of urban AA youth with persistent asthma were vitamin D deficient or insufficient. Given the emerging associations between low vitamin D levels and asthma, strong consideration should be given to routine vitamin D testing in urban AA youth, particularly those with asthma.

PMID:
20236657
PMCID:
PMC3328513
DOI:
10.1016/j.jpeds.2009.12.033
[PubMed - indexed for MEDLINE]
Free PMC Article
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