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BMC Infect Dis. 2010 Mar 16;10:69. doi: 10.1186/1471-2334-10-69.

The use of a geographic information system to identify a dairy goat farm as the most likely source of an urban Q-fever outbreak.

Author information

1
Centre for Infectious Disease Control, National Institute for Public Health and the Environment, A van Leeuwenhoeklaan 9, PO Box 1, 3720 BA Bilthoven, the Netherlands.

Abstract

BACKGROUND:

A Q-fever outbreak occurred in an urban area in the south of the Netherlands in May 2008. The distribution and timing of cases suggested a common source. We studied the spatial relationship between the residence locations of human cases and nearby small ruminant farms, of which one dairy goat farm had experienced abortions due to Q-fever since mid April 2008. A generic geographic information system (GIS) was used to develop a method for source detection in the still evolving major epidemic of Q-fever in the Netherlands.

METHODS:

All notified Q-fever cases in the area were interviewed. Postal codes of cases and of small ruminant farms (size >40 animals) located within 5 kilometres of the cluster area were geo-referenced as point locations in a GIS-model. For each farm, attack rates and relative risks were calculated for 5 concentric zones adding 1 kilometre at a time, using the 5-10 kilometres zone as reference. These data were linked to the results of veterinary investigations.

RESULTS:

Persons living within 2 kilometres of an affected dairy goat farm (>400 animals) had a much higher risk for Q-fever than those living more than 5 kilometres away (Relative risk 31.1 [95% CI 16.4-59.1]).

CONCLUSIONS:

The study supported the hypothesis that a single dairy goat farm was the source of the human outbreak. GIS-based attack rate analysis is a promising tool for source detection in outbreaks of human Q-fever.

PMID:
20230650
PMCID:
PMC2848044
DOI:
10.1186/1471-2334-10-69
[Indexed for MEDLINE]
Free PMC Article
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