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Surg Radiol Anat. 2010 Dec;32(10):989-95. doi: 10.1007/s00276-010-0650-4. Epub 2010 Mar 14.

On two equations about brain volume, cranial capacity and age.

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Service de Chirurgie Maxillofaciale, Centre Hospitalier Universitaire Pellegrin, Place Amélie Raba Léon, 33076, Bordeaux, France.



We decided to study the relationship between brain volume and cranial capacity and the relationship between brain volume and age on a series of CT from healthy adults.


Fifty-eight healthy volunteers (27 women, 31 men, age range 18-95 years) were examined using our imaging protocols. The volunteers had no present or past neuropsychiatric illness and no abuse of alcohol or illicit drugs.


Mean intracranial volume was 1,384.6 cm(3) (standard deviation = 135.27, range 1,106-1,656) and mean brain volume was 1,201.0 cm(3) (standard deviation = 142.52, range 791-1,500). Linear regression between brain volume and cranial capacity yielded this formula: brain volume = 182.3 + 0.7 × cranial capacity. Multivariate analysis yielded a relationship between cranial capacity, brain volume and age as follows: brain volume = 396.5-3.5 × age + 0.7 × cranial capacity.


This study could be supplemented by the collection of data such as, the size of the individuals in order to study the relationship between size of the brain and stature because this relation remains unclear.

[Indexed for MEDLINE]

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