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Mol Cell. 2010 Mar 12;37(5):591-2. doi: 10.1016/j.molcel.2010.02.001.

Transferring death: a role for tRNA in apoptosis regulation.

Author information

1
Program in Apoptosis and Cell Death Research, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

Abstract

Cytochrome c from mitochondria significantly accelerates the apoptotic process. In this issue of Molecular Cell, Mei et al. show that cytochrome c is itself regulated by binding to tRNA, providing an unanticipated level of control of cell fate decisions.

PMID:
20227362
DOI:
10.1016/j.molcel.2010.02.001
[Indexed for MEDLINE]
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