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Allergy Asthma Immunol Res. 2009 Oct;1(1):45-7. doi: 10.4168/aair.2009.1.1.45. Epub 2009 Sep 25.

Occupational asthma caused by inhalation of bovine serum albumin powder.

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Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea.


Bovine serum albumin (BSA), which is present in bovine plasma, is one of the major allergens affecting patients with food allergies induced by milk and meat. It is also commonly used in research laboratories. Although some reports have documented food allergies associated with BSA, BSA-induced occupational asthma has not been reported. We report a case of occupational asthma and rhinitis in a laboratory worker caused by the inhalation of BSA powder, in which an IgE-mediated response was suggested as the pathogenic mechanism.


bovine serum albumin (BSA); milk allergy; occupational asthma

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