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Bioinformatics. 2010 May 1;26(9):1273-5. doi: 10.1093/bioinformatics/btq109. Epub 2010 Mar 11.

TiSGeD: a database for tissue-specific genes.

Author information

1
Key Laboratory for Cell Biology and Tumor Cell Engineering, the Ministry of Education of China, School of Life Sciences, Fujian, P R China.

Abstract

The tissue-specific genes are a group of genes whose function and expression are preferred in one or several tissues/cell types. Identification of these genes helps better understanding of tissue-gene relationship, etiology and discovery of novel tissue-specific drug targets. In this study, a statistical method is introduced to detect tissue-specific genes from more than 123 125 gene expression profiles over 107 human tissues, 67 mouse tissues and 30 rat tissues. As a result, a novel subject-specialized repository, namely the tissue-specific genes database (TiSGeD), is developed to represent the analyzed results. Auxiliary information of tissue-specific genes was also collected from biomedical literatures.

AVAILABILITY:

http://bioinf.xmu.edu.cn/databases/TiSGeD/index.html.

PMID:
20223836
PMCID:
PMC2859128
DOI:
10.1093/bioinformatics/btq109
[Indexed for MEDLINE]
Free PMC Article

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