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Items: 1 to 20 of 62

1.

Genetic polymorphisms of CYP1A2, CYP3A4, CYP3A5, pregnane/steroid X receptor and constitutive androstane receptor in 207 healthy Spanish volunteers.

Oliver P, Lubomirov R, Carcas A.

Clin Chem Lab Med. 2010 May;48(5):635-9. doi: 10.1515/CCLM.2010.130.

PMID:
20218903
2.

Effect of oncostatin M on uridine diphosphate-5'-glucuronosyltransferase 1A1 through cross talk with constitutive androstane receptor.

Masuyama H, Nakatsukasa H, Hiramatsu Y.

Mol Endocrinol. 2010 Apr;24(4):745-53. doi: 10.1210/me.2009-0478. Epub 2010 Mar 2.

3.

Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3).

Mutoh S, Osabe M, Inoue K, Moore R, Pedersen L, Perera L, Rebolloso Y, Sueyoshi T, Negishi M.

J Biol Chem. 2009 Dec 11;284(50):34785-92. doi: 10.1074/jbc.M109.048108. Epub 2009 Oct 26.

4.

Association of a single nucleotide polymorphism in the constitutive androstane receptor gene with bone mineral density.

Urano T, Usui T, Shiraki M, Ouchi Y, Inoue S.

Geriatr Gerontol Int. 2009 Sep;9(3):235-41. doi: 10.1111/j.1447-0594.2009.00527.x.

PMID:
19702932
5.

Constitutive androstane receptor transcriptionally activates human CYP1A1 and CYP1A2 genes through a common regulatory element in the 5'-flanking region.

Yoshinari K, Yoda N, Toriyabe T, Yamazoe Y.

Biochem Pharmacol. 2010 Jan 15;79(2):261-9. doi: 10.1016/j.bcp.2009.08.008. Epub 2009 Aug 12.

PMID:
19682433
6.

Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress.

Osabe M, Sugatani J, Takemura A, Kurosawa M, Yamazaki Y, Ikari A, Miwa M.

FEBS Lett. 2009 Mar 4;583(5):885-9. doi: 10.1016/j.febslet.2009.01.051. Epub 2009 Feb 6.

8.

Specific inhibition of transcriptional activity of the constitutive androstane receptor (CAR) by the splicing factor SF3a3.

Yun HJ, Kwon J, Seol W.

Biol Chem. 2008 Oct;389(10):1313-8. doi: 10.1515/BC.2008.149.

PMID:
18713018
9.

ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: implications in hepatic stress responses.

Pascual M, Gómez-Lechón MJ, Castell JV, Jover R.

Drug Metab Dispos. 2008 Jun;36(6):1063-72. doi: 10.1124/dmd.107.019380. Epub 2008 Mar 10.

10.

Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation.

Osabe M, Sugatani J, Takemura A, Yamazaki Y, Ikari A, Kitamura N, Negishi M, Miwa M.

Biochem Biophys Res Commun. 2008 May 16;369(4):1027-33. doi: 10.1016/j.bbrc.2008.02.140. Epub 2008 Mar 10.

PMID:
18331826
11.

The roles of nuclear receptors CAR and PXR in hepatic energy metabolism.

Konno Y, Negishi M, Kodama S.

Drug Metab Pharmacokinet. 2008;23(1):8-13. Review.

12.

Nuclear receptor CAR requires early growth response 1 to activate the human cytochrome P450 2B6 gene.

Inoue K, Negishi M.

J Biol Chem. 2008 Apr 18;283(16):10425-32. doi: 10.1074/jbc.M800729200. Epub 2008 Feb 25.

13.

Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.

Kiyotani K, Mushiroda T, Kubo M, Zembutsu H, Sugiyama Y, Nakamura Y.

Cancer Sci. 2008 May;99(5):967-72. doi: 10.1111/j.1349-7006.2008.00765.x. Epub 2008 Feb 19.

14.

PPP1R16A, the membrane subunit of protein phosphatase 1beta, signals nuclear translocation of the nuclear receptor constitutive active/androstane receptor.

Sueyoshi T, Moore R, Sugatani J, Matsumura Y, Negishi M.

Mol Pharmacol. 2008 Apr;73(4):1113-21. doi: 10.1124/mol.107.042960. Epub 2008 Jan 17.

15.

Pharmacogenetics of the constitutive androstane receptor.

Lamba JK.

Pharmacogenomics. 2008 Jan;9(1):71-83. Review.

PMID:
18154449
16.
17.

Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.

Guo D, Sarkar J, Suino-Powell K, Xu Y, Matsumoto K, Jia Y, Yu S, Khare S, Haldar K, Rao MS, Foreman JE, Monga SP, Peters JM, Xu HE, Reddy JK.

J Biol Chem. 2007 Dec 14;282(50):36766-76. Epub 2007 Oct 25.

18.

Regulation of the human cathepsin E gene by the constitutive androstane receptor.

Page JL, Strom SC, Omiecinski CJ.

Arch Biochem Biophys. 2007 Nov 1;467(1):132-8. Epub 2007 Aug 19.

19.

PXR, CAR and HNF4alpha genotypes and their association with pharmacokinetics and pharmacodynamics of docetaxel and doxorubicin in Asian patients.

Hor SY, Lee SC, Wong CI, Lim YW, Lim RC, Wang LZ, Fan L, Guo JY, Lee HS, Goh BC, Tan T.

Pharmacogenomics J. 2008 Apr;8(2):139-46. Epub 2007 Sep 18.

PMID:
17876342
20.

Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver.

Patel RD, Hollingshead BD, Omiecinski CJ, Perdew GH.

Hepatology. 2007 Jul;46(1):209-18.

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