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J Biomed Opt. 2010 Jan-Feb;15(1):016006. doi: 10.1117/1.3290818.

Real-time diffuse optical tomography based on structured illumination.

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1
Ecole Polytechnique de Montréal, Département de Génie Electrique, Montréal, Québec, Canada.

Abstract

A new optical acquisition scheme based on a pair of digital micromirror devices is developed and applied to three-dimensional tomographic imaging of turbid media. By using pairs of illumination-detection patterns with a single detector, we were able to perform high-resolution quantitative volumetric imaging of absorption heterogeneities embedded in optically thick samples. Additionally, a tomographic reconstruction algorithm was implemented on a graphical processor unit to provide optical reconstructions at a frame rate of 2 Hz. The structured illumination method proposed in this work has significant cost advantages over camera systems, as only a single detector is required. This configuration also has the potential to increase frame rate.

PMID:
20210452
DOI:
10.1117/1.3290818
[Indexed for MEDLINE]
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