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J Int Assoc Physicians AIDS Care (Chic). 2010 Mar-Apr;9(2):98-103. doi: 10.1177/1545109710361383. Epub 2010 Mar 5.

Indicators of adherence to antiretroviral therapy treatment among HIV/AIDS patients in 5 African countries.

Author information

1
Institute of Human Virology of the University of Maryland School of Medicine, 725 West Lombard Street, Baltimore, MD 21201, USA. metienne@ihv.umaryland.edu

Abstract

As the HIV epidemic threatens the social fabric of countries struggling with HIV prevalence rates as high as 10% to 30%, access to antiretroviral therapy (ART) alone is only the beginning of the clinical challenge. There is a need to identify adherence indicators that will ensure long-term treatment success. A cross-sectional review of 921 adult patients on ART for at least 1 year was conducted. Through an administered adherence survey, key indicators were found to be highly correlated with patient adherence. The adherence rate in this sample was 72% after being on treatment for an average of 15 months. This data suggest that having a high perceived quality of care and owning one's own home positively affected patients' adherence. Indicators such as alcohol use in the last month and a high level of depression negatively affected patients' adherence. Targeting specific indicators for specific interventions will guard against nonadherence, leading to treatment failure.

PMID:
20207981
DOI:
10.1177/1545109710361383
[Indexed for MEDLINE]

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