Send to

Choose Destination
Mol Biol (Mosk). 2010 Jan-Feb;44(1):140-51.

[Attenuation regulation of amino acid and amino acyl-tRNA biosynthetic operons in bacteria: comparative genomics analysis].

[Article in Russian]


We performed a large-scale search for attenuation regulation in bacteria based on two original computer programs modeling attenuation regulation and multiple alignment along a phylogenetic tree. The programs are available from Candidate attenuations are predicted in many bacteria from alpha-, beta-, gamma-, delta-proteobacteria, Actinobacteria, Bacteroidetes/Chlorobi, Firmicutes and Thermotogae; in Cloroflexi--upstream genes hisG, hisZ, hisS, pheA, pheST, trpEG, trpA, trpB, trpE, trpS, thrA, thrS, leuA, leuS, ilvB, ilvI, ilvA, ilvC, ilvD, ilvG. Other bacterial taxa were not predicted to have attenuation; searches were conducted across all bacterial genomes contained in GenBank, NCBI. Evolution of attenuation is discussed.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center