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J Chemother. 1991 Feb;3(1):13-5.

In-vitro comparative activity of fluconazole and other antifungal agents against Blastoschizomyces capitatus.

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Patologia Medica II, Istituto di Clinica Medica VI, Università La Sapienza, Roma, Italy.


Blastoschizomyces capitatus represents an emerging fungal pathogen in acute leukemia patients. The susceptibility to amphotericin B, 5-fluorocytosine, ketoconazole and fluconazole of nine clinical isolates was evaluated. A specific medium (high resolution medium) was used for testing fluconazole. This agent and 5-fluorocytosine were at least four- to eight-fold more active than amphotericin B and ketoconazole against all isolates but one.

[Indexed for MEDLINE]

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