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Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2010 Apr;53(4):319-25. doi: 10.1007/s00103-010-1029-8.

[Medication dependency and physician's role].

[Article in German]

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LWL-Kliniken Warstein und Lippstadt, Franz-Hegemann-Str. 23, 59581, Warstein, Deutschland.


The administration of benzodiazepines in suicidal, anxious, or agitated patients with depression is common international practice. Nevertheless, the prescription of BZDs is recommended to be limited to a period of a few weeks. There are several epidemiological studies about the situation in Germany, but many questions are still unanswered. The BfArM sought a new method to track prescription of medications with the risk to induce dependency. The present article describes the methodology and the early results of the pilot study. As a new approach, data from a processing center for pharmacies were used; patient-years, a risk scale with six steps, and diazepam-equivalence dose instead of defined daily dose were used for the analysis. About 35% of prescriptions were long-term treatment. Even if several physicians prescribe the medication, the main physician prescribing the medication can identify the risk level of the patient in 80-90% of cases.

[Indexed for MEDLINE]

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