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Arch Pathol Lab Med. 2010 Mar;134(3):378-92. doi: 10.1043/1543-2165-134.3.378.

Pseudoneoplasms of the gastrointestinal tract.

Author information

1
Mayo Clinic, Scottsdale, Arizona 85259, USA. depetris.giovanni@mayo.edu

Abstract

CONTEXT:

The pathologist plays the leading role in distinguishing pseudoneoplasms from truly neoplastic lesions in the gastrointestinal tract.

OBJECTIVE:

This review was conducted to heighten awareness of pseudoneoplasms, to help differentiate among the various types of pseudoneoplasms, and to help distinguish pseudoneoplasms from malignancies.

DATA SOURCES:

This review is based on the medical literature on pseudoneoplasms in MEDLINE and the authors' own experiences. Reference lists of retrieved articles were also reviewed to identify additional articles.

CONCLUSIONS:

A classification of pseudoneoplasms, according to the mechanism of injury to the gastrointestinal tract, morphologic patterns, and heterotopia, may be useful in providing a diagnostic framework in which ancillary techniques often have a diagnostic role. Several pseudoneoplasms may be closely associated with true neoplasms (eg, malakoplakia, prolapsetype lesions) because of the nonspecific nature of the response of the intestine to injury.

PMID:
20196666
DOI:
10.1043/1543-2165-134.3.378
[Indexed for MEDLINE]

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