Abstract
Pharmacology of MMP13 and MMP13 selective inhibitors is reviewed.
© 2010 Wiley Periodicals, Inc.
MeSH terms
-
Allosteric Site
-
Animals
-
Cartilage / metabolism
-
Collagen / chemistry
-
Drug Design
-
Gene Expression Regulation, Enzymologic
-
Humans
-
Inflammation
-
Kinetics
-
Matrix Metalloproteinase Inhibitors*
-
Mice
-
Mice, Knockout
-
Osteoarthritis / drug therapy*
-
Protease Inhibitors / chemistry
-
Protease Inhibitors / pharmacology*
-
Rats
Substances
-
Matrix Metalloproteinase Inhibitors
-
Protease Inhibitors
-
Collagen