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Nat Methods. 2010 Mar;7(3 Suppl):S42-55. doi: 10.1038/nmeth.1427. Epub 2010 Mar 1.

Visualization of macromolecular structures.

Author information

1
European Molecular Biology Laboratory, Heidelberg, Germany. sean.odonoghue@embl.de

Abstract

Structural biology is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. Visualization is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing three-dimensional structures can provide insight and describe available methods and tools.

PMID:
20195256
DOI:
10.1038/nmeth.1427
[Indexed for MEDLINE]

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