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Curr Genomics. 2009 Sep;10(6):388-401. doi: 10.2174/138920209789177638.

Review of peak detection algorithms in liquid-chromatography-mass spectrometry.

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1
Dept. of ECE, University of Texas at San Antonio, San Antonio, TX 78249, USA.

Abstract

In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief introduction to LC/MS is followed by a description of the major processing steps in LC/MS. Specifically, the problem of peak detection is formulated and various peak detection algorithms are described and compared.

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