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Bioinformatics. 2010 Apr 15;26(8):1129-30. doi: 10.1093/bioinformatics/btq089. Epub 2010 Feb 25.

BioNet: an R-Package for the functional analysis of biological networks.

Author information

1
Department of Bioinformatics, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

Abstract

MOTIVATION:

Increasing quantity and quality of data in transcriptomics and interactomics create the need for integrative approaches to network analysis. Here, we present a comprehensive R-package for the analysis of biological networks including an exact and a heuristic approach to identify functional modules.

RESULTS:

The BioNet package provides an extensive framework for integrated network analysis in R. This includes the statistics for the integration of transcriptomic and functional data with biological networks, the scoring of nodes as well as methods for network search and visualization.

AVAILABILITY:

The BioNet package and a tutorial are available from http://bionet.bioapps.biozentrum.uni-wuerzburg.de.

PMID:
20189939
DOI:
10.1093/bioinformatics/btq089
[Indexed for MEDLINE]

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