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Biochim Biophys Acta. 2010 Aug;1806(1):7-17. doi: 10.1016/j.bbcan.2010.02.001. Epub 2010 Feb 23.

T regulatory cells, the evolution of targeted immunotherapy.

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1
Department of Cellular and Molecular Medicine, St George's University of London, UK.

Abstract

T regulatory cells are able to suppress anti-tumour immunity in pre-clinical models and in patients. This review highlights the important discoveries in Treg immunology critical to the evolution of targeted immunotherapy. We also describe the therapeutic applications that are currently being assessed and their future potential.

PMID:
20188145
DOI:
10.1016/j.bbcan.2010.02.001
[Indexed for MEDLINE]
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