Objective: To review the research and delivery methods of growth factors in tendon injuries, and to point out the problems at present as well as to predict the trend of development in this field.
Methods: Domestic and international literature concerning growth factors to enhance tendon and ligament healing in recent years was extensively reviewed and thoroughly analyzed.
Results: Cell growth factor could promote tendon healing, improve the mechanical properties as well as reduce the adhesion postoperatively. The use of transgenic technology mediating cell factors to promote tendon repair shows its advantages in many ways.
Conclusion: The growth factors play a vital role in tendon healing. Reasonable treatment of growth factors through direct application or gene transfer techniques is of great value for the healing process.