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Int J Eat Disord. 2011 Apr;44(3):269-75. doi: 10.1002/eat.20807.

Aripiprazole in anorexia nervosa and low-weight bulimia nervosa: case reports.

Author information

1
Department of Psychiatry, University of California San Diego, San Diego, California, USA.

Abstract

OBJECTIVE:

There has been much interest in the use of atypical antipsychotics in anorexia nervosa (AN). However, newer, more weight-neutral medications have not been studied in AN, and there are no reports of the use of antipsychotics in bulimia nervosa (BN).

METHOD:

We report on the treatment of eight patients (five with AN and three with BN) with aripiprazole for time periods of four months to more than three years.

RESULTS:

All individuals had reduced distress around eating, fewer obsessional thoughts about food, weight and body image, significant lessening of eating-disordered behaviors, and gradual weight restoration where appropriate. Depression, generalized anxiety, and cognitive flexibility improved as well.

DISCUSSION:

In summary, these findings support the need to perform controlled trials of aripiprazole in AN and BN.

PMID:
20186719
DOI:
10.1002/eat.20807
[Indexed for MEDLINE]

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